Functional Medicine

Bacillopeptidase F: Its Impact on Metabolic Syndrome Disorder

By Erik Goldman

Metabolic disorders, especially overweight and obesity, diabetes, and dyslipidemia are some of the most common illnesses all over the world, carrying a high burden of cardiovascular morbidity and mortality. In this free webinar, renowned integrative physician Fred Pescatore, MD, will share the science on a soy-derived fibrinolytic enzyme called Bacillopeptidase F, which is shown to […]

Who’s at Risk for High Uric Acid?

By Kristen Schepker, Assistant Editor

Serum uric acid measurements are the definitive indicators of uric acid elevation, but a thorough assessment of diet and lifestyle factors can also provide many clues about who is likely to develop uric acid problems down the road, said Dr. Perlmutter. He recommended asking patients about the following factors: Fruit juice (any kind) consumption Intake […]

Fine-Tuning the Digestive Symphony

By Russell Jaffe, MD, Contributing Writer

I like to think of digestion as a magnificent symphony in which a diverse array of organs, bacteria, and biochemicals work in concert to transform the foods we eat into the nutrients and energy we need. If any instrument is out of tune, the music suffers. This notion of the digestive system as an orchestra […]

Nicotinamide Riboside Combo Improves Hepatic Profiles in NAFLD

By August West, Contributing Writer

Daily supplementation with a fixed dose combination of nicotinamide riboside, L-carnitine, L-serine, and N-acetyl cysteine significantly reduced liver fat, quelled oxidative stress, and improved liver enzyme profiles in a cohort of 31 patients with non-alcoholic fatty liver disease (NAFLD). Defined as hepatic fat accumulation of 5% or more, unrelated to alcohol consumption or other liver […]

Long Haul Covid: A Variant of Post-Viral Syndrome

By Jacob Teitelbaum, MD, Contributing Writer

Long-haul Covid has unique features, but essentially, it is a variant of post-viral syndrome. That’s good news because many of the features of post-viral syndrome are easily treated. Between 20% and 25% of all Covid patients have persistent symptoms of some sort. Those numbers are similar to what we see with Epstein-Barr virus (EBV) and […]

Clearing the Fog Around Mast Cell Activation Syndrome

By Erik Goldman

Mast cell activation syndrome—a multi-system disorder characterized by aberrant activity of these key immune cells—is widely prevalent, and on the rise as the world becomes more toxic, infectious, and stressful, says Tania Tyles Dempsey, MD, a clinician who specializes in this common but mis-diagnosed problem. The syndrome differs from mastocytosis or mast cell cancers in […]

BREESI & QUEESI: Tips for Diagnosing MCAS

By Erik Goldman

Mast cell activation syndrome (MCAS) is inherently complex, and it can manifest in a bewildering number of ways. Patients may experience waxing and waning symptoms in seemingly unrelated organ systems, with no obvious pattern. MCAS overlaps with other chronic syndromes such as Ehlers-Danlos (EDS), Postural Orthostatic Tachycardia Syndrome (POTS), and chronic fatigue/fibromyalgia. It’s a complicated […]

Processed Foods & Energy Drinks: A Public Health Emergency

By Chad Larson, NMD, DC, and Mark R. Engelman, MD, Contributing Writers

Highly processed foods and energy drinks do more harm than good—and Americans have a huge appetite for them. That’s bad news for the future health of the country.  According to a new analysis of data from nearly 41,000 US adults, consumption of ultra-processed foods rose markedly from 2001 to 2018, accounting for nearly 60% of […]

Glycocalyx Restoration is Key for Lowering CVD Risk

By Erik Goldman

Repair of the endothelial glycocalyx is a vital element in the restoration of cardiovascular health, according to Mark Houston, MD, director of the Hypertension Institute at Saint Thomas West Hospital, Nashville. The endothelial glycocalyx (EGX) —literally “sugar coating” in Greek—is a very thin gel-like layer that lines the luminal surface of the blood vessels. It […]

Uric Acid is Detrimental to Gut Health

By Kristen Schepker

“People who suffer from chronic elevated uric acid tend to harbor unhealthy biomes,” says neurologist David Perlmutter, MD.

In his latest book, Drop Acid: The Surprising New Science of Uric Acid, Perlmutter presents several studies showing that adverse changes in the gut microbiome directly relate to our ability to metabolize and eliminate uric acid (UA).

The intricate interplay between hyperuricemia and the gut microbiome is still a relatively new field of research. But it has already led to some interesting discoveries.