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The Uncertain Multigenerational Implications of PFAS

By Nicole Williams

Per- and polyfluoroalkyl substances (PFAS) also known as “forever chemicals” are increasingly common water pollutants. Linked to various types of cancer, endocrine diseases, and immunologic disorders, PFAS can enter amniotic fluid, cord blood, and breast milk, raising neonatal exposure levels. (Image: Yuri A/Peopleimages.com)

(This article was originally published on January 27, 2025 by www.undark.org)

My son was born in late 2019. A few months later, early one morning, I found myself looking into his eyes as he nursed and I wondered if I was doing the right thing. Trying to ignore my nagging worry, I continued nursing him, pushing off the uncertainty until the next feeding.

I am a third-generation resident of Westfield, Massachusetts, a city known for its good school system, robust athletics program, and local continuity — the type of place where you share the same high school German teacher as your parent. Westfield is also known for its contaminated drinking water. It’s a decades-old problem that recent research shows may have an especially harmful impact on developing fetuses and infants: the contamination of per- and polyfluoroalkyl substances, commonly known as PFAS, or forever chemicals. And in the late summer of 2024, I joined other families in an ongoing lawsuit against the company that manufactured the chemicals, 3M.

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Featured Articles

Texas Lawmakers Rally Around State Level ‘Mini-MAHA’ Bill

Written by Janet Gulland, Contributing Writer

The Texas state senate voted unanimously in favor of a health and wellness bill that—if passed by the state’s house—will mandate daily exercise and nutrition education in public schools, require metabolic health training for all medical professionals, and force food makers to label products containing toxic additives banned in other countries. The goals of SB […]

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HPC Video

The Gut-GLP-1 Connection: The role of Akkermansia & other novel probiotic strains in satiety and cravings

Written by Erik Goldman

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Akkermansia muciniphila, a key player in the gut microbiome, has emerged as a significant influencer of GLP-1, a hormone with profound implications for metabolic health.

Learn from Adam Perlman, MD, MPH, Chief Medical Officer of Pendulum Therapeutics, about the latest research uncovering the impact of A. muciniphila, C.butyricum, B.infantis and other novel microbial strains on GLP-1 signaling, satiety, cravings, and the potential of probiotics for metabolic disorders.

Learning objectives: 

  1. Understand the role of GLP-1 (Glucagon-Like Peptide-1) in gut metabolism and its significance in metabolic health
  2. Identify the mechanisms by which targeted probiotics can influence GLP-1 secretion and metabolism
  3. Detail the science and evidence for the use of a synbiotic specifically formulated to improve gut health and food cravings

Adam Perlman, MD, MPH is the Chief Medical Officer at Pendulum Therapeutics. He formerly served as the Director of Integrative Health and Wellbeing at Mayo Clinic, Florida, and Medical Director for Employee Wellbeing. Prior to that, he was Associate Vice President for Health and Wellness for the Duke University Health System, overseeing Duke Integrative Medicine and the Duke Diet Center. Dr. Perlman received his BA from Tufts University and his MD from Boston University School of Medicine, completing residencies in Internal Medicine and Preventive Medicine as well as a General Internal Medicine Research Fellowship at Boston Medical Center. He earned an MPH from the Boston University School of Public Health.

Sponsored by: PENDULUM HEALTH

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