By Erik Goldman
A small but compelling case series published last year suggests that mega-doses of vitamin D can yield dramatic improvement in the severity of longstanding psoriasis. And by “mega,” we mean doses as high as 60,000 IU per day.
Renu Mahtani, a physician at the Autoimmunity Treatment Centre, Pune, India, together with Pradeep M.K. Nair of the Sant Hirdaram Medical College of Naturopathy in Bhopal, treated six patients—five women and one man—with high-dose oral vitamin D (25-hydroxy cholecalciferol) for periods of 2-6 months, in the absence of other concomitant psoriasis therapies.
The patients ranged in age from 48 to 63 years, and all had moderate to severe psoriasis for between 2-30 years. Three had psoriasis vulgaris, and the others had the palmoplantar form of the disease.
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