Functional Medicine

Mood by Microbe: Stress Response and the Gut-Brain Axis

By Erik Goldman

Multiple converging lines of evidence have shown that the primary cause of chronic systemic inflammation may be the dysfunction of the gut-brain axis. In this presentation, renowned integrative psychiatrist, David Scheiderer, MD, reviews the links between dysbiosis, meta-inflammation, and various psychiatric conditions. Dr. Scheiderer discusses the impact of medications, alcohol, diet, and lifestyle on the […]

Optimizing the Brain-Microbiome Axis

By Erik Goldman

The promise of the “psychobiotic revolution” is that many of the underlying drivers of chronic mental illness can be reversed with relatively simple interventions. “We cannot change the genes in our cells. But we can change the genes in our microbiota. That can have a positive—or a negative—health benefit,” says Ted Dinan, MD, PhD, a […]

Psychobiotics: Your Brain on Friendly Flora

By Grant Jackson, MD

The typical human body contains roughly 1.5 kilograms of microorganisms. That’s about equal in weight to the average human brain. It’s an interesting equivalence, given what we are learning about the myriad ways in which the gut microbiome influences the brain and central nervous system. Many common mental illnesses, including severe depression and anxiety, are […]

The Role of Micronutrients & Probiotics in Immune Health for Children

By Erik Goldman

The immune system is an elegant and complex set of cells, proteins, and tissues designed to protect our bodies from infections, both minor and life-threatening. Both the innate and acquired immune systems are dependent upon healthy nutrition, a healthy gut microbiome, adequate rest, and management of stress. The transfer of maternal microbiota is very closely linked to a […]

Maintaining Resilience by Supporting Healthy Mitochondrial Function

By Erik Goldman

In recent years, researchers and medical practitioners alike have taken interest in a particular molecule known to be the master regulator of cellular metabolism — nicotinamide adenine dinucleotide (NAD+). NAD+ is a ubiquitous coenzyme involved in hundreds of metabolic processes, including: mitochondrial energy production, glycolysis, and DNA synthesis and repair. It also plays a vital […]

Rx Omega-3 No Better Than Corn Oil for Preventing CV Events

By Erik Goldman

Astra-Zeneca’s Epanova—a highly processed carboxylic acid form of EPA and DHA– failed to deliver the expected reduction in major cardiovascular events observed during 2019’s REDUCE-IT trial using the fish oil-based Vascepa EPA. The just-published multicenter STRENGTH trial  ( (STatin Residual Risk Reduction With EpaNova in HiGh CV Risk PatienTs With Hypertriglyceridemia) randomized 13,078 high-risk patients […]

Providing Help at the Intersection of Pain Place & Depression Boulevard

By Russell Jaffe, MD

Depression, anxiety, and chronic pain frequently co-occur, though the connection between them is not always apparent at the outset. While most people experience physical pain at some point in their lives, in those with depression or anxiety, pain can become particularly intense and hard to treat. People suffering from depression, for example, tend to experience more severe […]

Functional Med Practices Show Resilience Through the COVID Storm

By Erik Goldman

Data from a survey of over 3,500 functional, integrative, and metabolic medicine practitioners suggests that most are navigating the stormy post-COVID waters with considerable resilience. Compared with other physician surveys posted over the course of the last 9 months, the functional and holistic clinicians in this cohort report fewer practice closures and less income loss. […]

How Body Recomposition Can Revolutionize Your Patients’ Health

By Stacy Collier

Body recomposition refers to the process of gaining muscle and losing fat simultaneously. It is not a specific diet or exercise plan. Rather, it is a set of principles and practices that help people build muscle and strength, lose fat, and establish healthy eating and exercise habits. When followign the 5 main pillars of body […]

Bolstering Mucosal Barriers is Key to Boosting Immunity

By Mark Engelman, MD & Chad Larson, NMD, DC

The COVID-19 pandemic, along with the onset of flu season, have a lot of people thinking about their immune systems, and seeking ways to improve resilience to viruses and other types of infection. The best way to help patients strengthen their immunity is to work with them to optimize gut health and strengthen epithelial barriers. […]