Functional Medicine

Agmatine Attenuates Sciatica & Other Neuropathies

By Gad M. Gilad, PhD, Contributing Writer

Agmatine, a ubiquitous naturally occurring metabolite of arginine, was discovered in 1910. Yet, it took more than a century before researchers showed that this unique compound has clinically significant cytoprotective and neuroprotective properties. Recent work indicates that it can reduce pain associated with sciatica and other common forms of neuropathy.

Challenged by MS, the “Spice-Trekkers” Discover Their Own Culinary Medicine

By Ellen Kanner, Contributing Writer

Philippe and  Ethné de Vienne an explorer by nature. He and his wife Ethné travel the world, sourcing organic spices and herbs where they’re grown. That’s their job as the owners of the Montreal-based spice company, Épices de Cru. But five years ago, when Philippe was suddenly diagnosed with Multiple Sclerosis, their search took a very different turn–one that led to important discoveries about how to use foods and spices to alter the course of serious autoimmune diseases.

What Common Blood Tests Reveal About Cancer Risk

By Nalini Chilkov, LAc, OMD, Contributing Writer

While there is no simple blood test for predicting who will get cancer, there is a lot of information to be gleaned from basic blood work that, taken together, reveals much about an individual’s predispositions for many forms of cancer.

SAMe Equals Rx Drugs in Treatment of Depression

By Janet Gulland, Contributing Writer

A recent literature review of S-Adenosyl-methionine (SAMe) is shedding new light on this unique compound in the treatment of depression and other neuropsychiatric disorders. In some studies, SAMe was equivalent in efficacy to Tricyclic Antidepressants (TCAs) and Selective Serotonin Reuptake Inhibitors (SSRIs) in reducing symptoms and improving quality of life.

To Reverse Alzheimer’s, Seek its Triggers: An Interview with Dale Bredesen, MD

By Erik Goldman, Editor

Alzheimer’s disease is largely preventable, and often reversible. Those are bold statements, especially from a conventionally-trained neurologist. But Dale Bredesen, MD, is used to challenging orthodox views. In this in-depth interview article, Dr. Bredesen shares his perspective–drawn from more than 30 years’ clinical and research experience–on how to avert the “long goodbye” of dementia.

Can Strep Trigger OCD? Two Decades On, A Controversy Continues

By Francie Fitzgerald, Contributing Writer

More than 20 years since it was first described, PANDAS (Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal Infections) remains controversial.The recent emergence of a new diagnostic test panel has potential to provide biological evidence for the autoimmune process thought to trigger neuromotor symptoms observed in patients that fit the PANDAS/PANS description.

Is “Keto” the Key to Reversing Diabetes?

By Erik Goldman, Editor in Chief

A wave of recent studies show that in many cases, type 2 diabetes is partly or wholly reversible with high fat, very low carb ketogenic diets. But the process requires careful coaching, and should not be undertaken without good clinical guidance.

In Genomics, as in Life, the “80/20 Rule” Applies

By Liz Lipski, PhD, CNS

There’s a lot of hype around genomics these days. From a patient care perspective, it comes down to two basic questions: What types of tests give truly useful information? And, who benefits most from having the testing done? Thought leaders in the field gathered at Maryland University of Integrative Health for a three-day symposium on these issues.