Chronic Disease

The Aging Brain: Evidence-Based Interventions for Brain Health

By Erik Goldman

Age-associated cognitive decline is one of the nation’s most pressing health issues. Every day in the US, roughly 10,000 people reach their 65th birthdays. People over 65 years of age now represent almost 15% of the total population. Octogenarians are the fastest growing age bracket. As these trends continue, the need for effective clinical strategies […]

New Studies Affirm Core Tenets of Functional Medicine

By Janet Gulland, Contributing Writer

Among the core tenets of holistic and functional medicine are the ideas that lifestyle-based interventions aimed at mitigating root causes of chronic disease will improve clinical outcomes, and that this can reduce healthcare costs. These premises makes intuitive sense. But proving them on a healthcare system level has been challenging. Two recent studies provide significant […]

Building Youthful NAD+ Power with Precursors, Sirtuin-Activating Compounds & Methylation Support

By Erik Goldman

The depletion of Nicotinamide Adenine Dinucleotide (NAD+) over time has emerged as a central driver of much of the degenerative decline associated with aging. Depletion of NAD+ can negatively impact a multitude of core biochemical functions that may influence healthspan. Because NAD+ levels steadily drop with age, the repletion of this vital metabolic cofactor has […]

How Financial Stress Impacts the Immune System

By Kristen Schepker

A recent study of a group of hedge fund traders suggests that the immune system responds to financial stress as if it were a disease. The findings suggest a striking correlation between the human immune system and the volatility of entire financial systems, including the stock market.

Platelets: How to Keep Them In the “Goldilocks” Zone

By Russell Jaffe, MD, Contributing Writer

Platelets may be tiny—on average they’re about 20% of the diameter of red blood cells—but they have huge impact on our health and wellbeing. Beyond their obvious role in blood clotting and wound healing, they are also important players in the immune system. More than we realize, optimal health depends on the platelets doing their […]

Plant Sterols: An Effective Alternative For Statin-Intolerant Patients

By Janet Gulland, Contributing Writer

A recently published case series from the University of Chicago underscores the value of plant sterol supplements for managing elevated cholesterol in statin-intolerant patients at moderate to high risk for cardiovascular disease. While statin therapy with accompanying lifestyle modification remains the preferred conventional intervention for treating dyslipidemias and reducing cardiovascular risk, many patients do not […]

Immune System “Fingerprinting” A Key to Understanding Autoimmunity

By Mark R. Engelman, MD & Chad Larson, NMD, DC

A recent study published in the journal Arthritis and Rheumatology, shows that the prevalence of antinuclear antibodies (ANA)– the most common biomarker of autoimmunity–has increased considerably in the United States in recent years. Researcher Gregg E. Dinse and colleagues at Social & Scientific Systems, Durham, NC, examined the prevalence of ANA positivity in human subjects […]

Optimizing the Brain-Microbiome Axis

By Erik Goldman

The promise of the “psychobiotic revolution” is that many of the underlying drivers of chronic mental illness can be reversed with relatively simple interventions. “We cannot change the genes in our cells. But we can change the genes in our microbiota. That can have a positive—or a negative—health benefit,” says Ted Dinan, MD, PhD, a […]

Psychobiotics: Your Brain on Friendly Flora

By Grant Jackson, MD

The typical human body contains roughly 1.5 kilograms of microorganisms. That’s about equal in weight to the average human brain. It’s an interesting equivalence, given what we are learning about the myriad ways in which the gut microbiome influences the brain and central nervous system. Many common mental illnesses, including severe depression and anxiety, are […]