Functional Medicine

MTHFR Mutation: A Missing Piece in the Chronic Disease Puzzle

By Bianca Garilli, ND, Contributing Writer - Vol. 13, No. 2. , 2012

Methylenetetrahydrofolate reductase (MTHFR) is one of the most important enzymes in human physiology, having influence on at least as many biochemical processes as it has syllables in its name. Deficiencies in this enzyme increase the risk of CVD, several types of cancer, congenital defects, and inflammatory bowel disease. Fortunately, deficiencies are correctable with targeted supplementation.

Blood Viscosity: The Unifying Parameter In Cardiovascular Disease Risk

By Ralph E. Holsworth, Jr., DO & Jonathan V. Wright, MD - Vol. 13, No. 1. , 2012

Increased blood viscosity is the only biological parameter that has been linked with all of the other major heart disease risk factors, including high blood pressure, elevated LDL cholesterol, low HDL, type-II diabetes, metabolic syndrome, obesity, smoking, age, and male gender. Until recently, technological limitations made it impractical for doctors to measure this key risk factor. Fortunately, that’s changing.

Blood Viscosity: The Unifying Parameter In Cardiovascular Disease Risk

By Ralph E. Holsworth, Jr., DO & Jonathan V. Wright, MD - Vol. 13, No. 1. , 2012

Increased blood viscosity is the only biological parameter that has been linked with all of the other major heart disease risk factors, including high blood pressure, elevated LDL cholesterol, low HDL, type-II diabetes, metabolic syndrome, obesity, smoking, age, and male gender. Until recently, technological limitations made it impractical for doctors to measure this key risk factor. Fortunately, that’s changing.

Blood Viscosity: The Unifying Parameter In Cardiovascular Disease Risk

By Ralph E. Holsworth, Jr., DO & Jonathan V. Wright, MD - Vol. 13, No. 1. , 2012

Increased blood viscosity is the only biological parameter that has been linked with all of the other major heart disease risk factors, including high blood pressure, elevated LDL cholesterol, low HDL, type-II diabetes, metabolic syndrome, obesity, smoking, age, and male gender. Until recently, technological limitations made it impractical for doctors to measure this key risk factor. Fortunately, that’s changing.

Sublingual Immunotherapy: Allergy Relief Under Your Tongue

By Scott Rollins, MD / Contributing Writer - Vol. 11, No. 4. , 2010

 

Sublingual immunotherapy is a safe, highly effective alternative to injection-based treatments for managing allergies. Moreover, it enables primary care physicians to treat patients that they are currently referring out to specialists.

 

Who’s in Bed with the IOM? Vitamin D Report Prompts Conflict of Interest Suspicion

By Erik Goldman

The Institute of Medicine’s Nov. 30 consensus statement claiming most Americans do not need supplemental vitamin D—a position that runs counter to the views of many clinicians and researchers⎯has some folks wondering if committee members had preexisting biases or vested interests against supplementation.

It turns out that at least two members of the committee hold patents on synthetic vitamin D analogs in development or already on the market as prescription drugs, and significant relationships with companies involved in vitamin D drug development.

 

Telomeres, Aging, & Disease Prevention: Do Telomere-Targeted Treatments Have a Role in Clinical Practice?

By Stephen Holt, MD, PhD | Contributing Writer - Vol. 11, No. 3. , 2010

Telomeres—segments of chromosomes that prevent aberration or loss of genetic information during cell division—are among the hottest research topics these days, and they’ve become the focus of “anti-aging” and chronic disease prevention strategies. Like many areas of genetic research, the work on telomeres raises as many questions as it answers. Anti-aging specialist Dr. Stephen Holt explores the many nuances of telomere and telomerase research, offering his own clinically tested recommendations.