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Cardiovascular Health

Rethinking Alzheimer’s: The Role of Microglial Cells Is Key

By Erik Goldman

For decades, Alzheimer’s disease research, and the clinical approaches that derive from it, have been hyper-focused on amyloid-β and its deleterious effects. But despite billions spent, this line of work has yet to yield a single truly effective drug therapy. That’s because there’s far more to the Alzheimer’s equation than amyloid plaques. In fact, by […]

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To Help Patients Sleep, Ask the Right Questions

By Ron Grisanti, DC, Contributing Writer

Conventional medicine tends to view insomnia as an isolated problem — a nuisance symptom to be ameliorated. The solutions offered usually fall into three categories: Basic sleep hygiene advice: Recommendations like reducing screen time, keeping the bedroom dark, or sticking to a bedtime routine are helpful, but they are rarely enough on their own. For […]

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The Ultra-Damaging Effects of Ultra-Processed Foods

By John Neustadt, ND, Contributing Writer

We hear a lot of talk about ultra-processed foods (UPFs) these days. Though there is no officially recognized definition of “ultra-processed,” the term is widely used, and it has even become something of a political issue in recent months—-and with good reason. UPFs have become a dominant feature of the modern diet, accounting for about […]

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Mangos Improve Insulin Sensitivity In People at Risk for Diabetes

By Janet Gulland, Contributing Writer

Mangos. They’re cheery, packed with vitamin C and other nutrients, and though they’re quite sweet, they can improve insulin sensitivity in people at risk of type 2 diabetes. That’s the upshot of a recent clinical trial from researchers at the Clinical Nutrition Research Center at the Illinois Institute of Technology. Katherine Pett and colleagues studied […]

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Telomeres at the Crossroads of Neurological Health & Metabolic Syndrome

By Erik Goldman

Join us for an in-depth exploration of how telomere biology is reshaping our understanding of aging-related conditions. In this free webinar, Dr. Gordon Crozier—a renowned practitioner of integrative medicine and genetics-based healthcare—explains how telomeres influence cellular metabolism and genomic stability. The gradual shortening of these protective caps at the ends of chromosomes has been linked […]

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Clearing Up Misconceptions About Olive Oil

By Artemis Morris, ND, LAc

(This article was adapted for Holistic Primary Care from “5 Myths About Olive Oil on Dr. Kara Fitzgerald’s website). There is an old Cretan saying: “Το λάδι είναι το αίμα της γης.” It means, “Olive oil is the blood of the earth.” That tells us a lot, about both the inherent richness of olive oil, and the […]

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The Gut-GLP-1 Connection: The role of Akkermansia & other novel probiotic strains in satiety and cravings

By Erik Goldman

Akkermansia muciniphila, a key player in the gut microbiome, has emerged as a significant influencer of GLP-1, a hormone with profound implications for metabolic health. Learn from Adam Perlman, MD, MPH, Chief Medical Officer of Pendulum Therapeutics, about the latest research uncovering the impact of A. muciniphila, C.butyricum, B.infantis and other novel microbial strains on GLP-1 signaling, satiety, cravings, […]

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Folic Acid: Too Much of a Good Thing?

By Gil Winkelman, ND, Contributing Writer

It is time to rethink how we’re using folate, and its derivatives, methylfolate and folinic acid. Recent research suggests that people who routinely take more than 1000 μg of folic acid per day may be at increased risk of cognitive decline, asthma, impaired immune function, and certain types of cancer (Fardous AM, et al. Nutrients. […]

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A Good Relationship Gone Bad: Recognizing & Restoring Health in GI Candidiasis

By Erik Goldman

Candida is a commensal microorganism living in the digestive tract of the vast majority of our patients. For most, it causes no harm. But certain common lifestyle factors and medication exposures promote overgrowth of Candida species, leading to a fungal-predominant dysbiosis with sometimes severe systemic symptoms. Candidal overgrowth is often an important piece of the chronic illness […]

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Be Alert for Drug-Induced Magnesium Depletions

By Meg Sinclair, Staff Writer

Be on the lookout for drug-induced magnesium depletions. That’s one of the major messages from a comprehensive new paper on the clinical impact of magnesium deficiencies recently published in the New England Journal of Medicine. Many of the most widely prescribed drugs, including diuretics, proton pump inhibitors (PPIs), and certain antibiotics, can cause magnesium wasting. […]

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