Vitamins & Supplements

Maintaining Resilience by Supporting Healthy Mitochondrial Function

By Erik Goldman

In recent years, researchers and medical practitioners alike have taken interest in a particular molecule known to be the master regulator of cellular metabolism — nicotinamide adenine dinucleotide (NAD+). NAD+ is a ubiquitous coenzyme involved in hundreds of metabolic processes, including: mitochondrial energy production, glycolysis, and DNA synthesis and repair. It also plays a vital […]

Rx Omega-3 No Better Than Corn Oil for Preventing CV Events

By Erik Goldman

Astra-Zeneca’s Epanova—a highly processed carboxylic acid form of EPA and DHA– failed to deliver the expected reduction in major cardiovascular events observed during 2019’s REDUCE-IT trial using the fish oil-based Vascepa EPA. The just-published multicenter STRENGTH trial  ( (STatin Residual Risk Reduction With EpaNova in HiGh CV Risk PatienTs With Hypertriglyceridemia) randomized 13,078 high-risk patients […]

Two Paths for Optimizing Nitric Oxide Production

By Erik Goldman

There’s an old aphorism attributed to baseball great Yogi Berra: “When you come to a fork in the road, take it.” The New York Yankees legend said it while giving directions to his old friend, Joe Garagiola. He certainly was not talking about nutrition to improve nitric oxide production. But thanks to the development of […]

“Get On My Level” Raises Vitamin D Awareness in Minority Communities

By Erik Goldman

With its new “Get On My Level” campaign, the Organic & Natural Health Association hopes to help African American, Native American, and Hispanic American communities mitigate one of the biggest—and most modifiable–risk factors for COVID-19: Vitamin D deficiency. The program is focused on raising awareness about the connection between vitamin D deficiency, poor overall health, […]

The Brain-Gut-Microbiota Axis: A Primer for Clinicians

By Erik Goldman

The brain-gut-microbiota axis provides a bidirectional route of communication between the gut microbes and the brain. The axis involves the vagus nerve, short-chain fatty acids, tryptophan, cytokines and the hypothalamic-pituitary-adrenal axis. New evidence suggests that gut microbes are involved in neural development and function, both peripherally in the enteric nervous system and centrally in the […]

Nitric Oxide: The Body’s Best Medicine

By Erik Goldman

Nitric Oxide (NO) has been the topic of over 140,000 research articles.  The pinnacle of accomplishment in this field was the Nobel Prize in Medicine given to three American scientists for their work in discovering the nitric oxide pathway.  Since then, pharmaceutical and nutraceutical companies have been scrambling to create new products that harness the […]

IFM’s New COVID Course Spotlights Strategies for Resilience & Recovery

By Erik Goldman

Since the earliest days of the COVID-19 outbreak, the Institute for Functional Medicine has taken a lead in the effort to compile, evaluate and disseminate practical information on nutritional and botanical interventions for immune system resilience, risk mitigation, and recovery from infection. Headed by Patrick Hanaway, MD, IFM’s COVID-19 Task Force has also been helping […]

Probiotics & Digestive Diseases–Hope or Hype?

By Erik Goldman

Probiotics are consistently among the top 5 most popular categories of dietary supplements. US sales of probiotic products are expected to reach nearly $500 million this year, and could top $2.6 billion by mid-decade, according to Statista. There is good evidence that carefully selected probiotics offer myriad benefits for gastrointestinal as well as broader systemic […]

Herbs are Complex, Let’s Stop Over-Simplifying Them

By Erik Goldman

Botanical medicine has evolved extensively over the last 20 years, as public interest in medicinal herbs has grown, and the product development process has become more sophisticated. One of the major trends has been the focus on delivering highly concentrated forms of “active” compounds extracted from the myriad of molecules produced by plants. Over the […]