Viroid Obelisks: The Microbiome’s Microbiome?

By Erik Goldman

Obelisk S.s: A novel viroid-like entity discovered within Streptococcus sanguinis, a facultative anaerobe that is part of the normal oral flora. According to the Stanford University researchers who discovered them, Obelisks represent an entirely new phylogenic category (Image from: Zheludev IN, et al. 2024)

Just when you thought the microbiome couldn’t get any weirder, investigators at Stanford University have discovered a whole new dimension in the microbial universe: a category of distinct, self-replicating RNA sequences in and among bacteria of the human gut and oral microbiomes.

Named “Obelisks” owing to their circular rod-like structures, these peculiar bits of genetic information are unlike any genomic sequences in the known viral, bacterial, fungal, or animal worlds.

In discovering Obelisks, Nobel prize-winning geneticist Andrew Fire and his team believe they’ve opened an entirely new frontier in microbiology.

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Featured Articles

The Post-Viral Recovery Program Supplement Protocols

Written by Erik Goldman

The Long Covid nutritional protocol developed by the 10-member practitioner working group under the aegis of OvationLab and ANDHealth, is divided into two parts—Foundational Supplements aimed at improving overall health, and Specialty Supplements focused on the five main drivers of Long Covid: ACE2-mediated tissue damage; viral persistence; chronic inflammation; mitochondrial dysfunction; and microbiome/dysbiosis. The working […]

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For Disease Risk Reduction, Broc Rocks!

Written by Erik Goldman

Imagine if there were a drug that could reduce risk of cancer and cardiovascular disease by roughly 40%, without any adverse effects. Even better, people would only need to take it 2 or 3 times per week to obtain these preventive benefits. It turns out there is such a thing. It’s called broccoli. People who […]

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HPC Video

IBS & Osteoporosis - The BMP Connection

Written by Erik Goldman

Irritable Bowel Syndrome (IBS) and Osteoporosis are two of the most common conditions that integrative practitioners see among their patients. These disorders are actually related.

The common factor? Bone Morphogenic Proteins (BMPs)—a group of cytokines that play important roles in bone and joint homeostasis as well as in GI mucosal integrity.

In this free webinar, Cynthia Worden, DO, will explore the connections between IBS and Osteoporosis, and share new insights into the dual role of Bone Morphogenic Proteins in supporting patients with GI and bone health issues.

She’ll also describe her clinical experience with Ostinol®–the only BMP-complex available for oral supplementation.

During this webinar, you’ll learn about: 

  • The epidemiological relationship between IBS and Osteoporosis—and the rising rates of both conditions
  • The discovery of BMPs, their structure, and their function within Demineralized Bone Matrix
  • Mechanisms of action and observed clinical impact of BMPs
  • The practical benefits of BMPs in supporting patients with IBS and Osteoporosis
  • Case studies & clinical experience with Cyplexinol® Musculoskeletal Regenerative Nutrition

SPONSORED BY Regenerative Tissue Sciences, the professional sales division of ZyCal Bioceuticals Healthcare Co., Inc.

Cynthia Worden, DO, MSHPE, IFMCP earned her medical degree at Western University of Health Sciences in Pomona, CA in 2004. She also completed a teaching fellowship in Osteopathic Manipulation, a Master’s in Health Professions Education, and a Doctorate in Osteopathy.  Dr. Worden completed her Internship and Osteopathic Family Medicine residency training at Downey Regional Medical Center.

Following her training, she practiced Integrative Family Medicine at Creekside Family Practice in Portland, OR, for 10 years.  After discovering functional medicine, Dr. Worden realized it held many of the answers to her patient’s chronic medical conditions. She became a Certified Practitioner with the Institute for Functional Medicine (IFMCP) in 2016, after which she founded Bloom Functional Medicine in 2018.

Like many who practice functional medicine, Dr. Worden has faced her own health issues: Hashimoto’s and Crohn’s disease. Consequently, she has first-hand knowledge of how these conditions affect overall health and well-being. In her free time, she loves to spend time with her family and friends, and to continue her learning. She loves to cook, read, kayak, ski, hike, and travel.

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