Daily supplementation with a fixed dose combination of nicotinamide
riboside, L-carnitine, L-serine, and N-acetyl cysteine significantly reduced
liver fat, quelled oxidative stress, and improved liver enzyme profiles in a
cohort of 31 patients with non-alcoholic fatty liver disease (NAFLD).
Defined as hepatic fat accumulation of 5% or more, unrelated to alcohol
consumption or other liver diseases, NAFLD affects roughly one in four adults according to recent estimates. Incidence is on the rise, driven in part by
the close association of NAFLD with insulin resistance, diabetes, and obesity,
all of which are increasing globally.
“Current management strategies, including lifestyle modification, increased physical activity, and dietary intervention, have limited adherence and minimal prolonged success,” wrote Mujdat Zeybel, of the NIHR Nottingham Biomedical Research Center, UK, and lead author of the new study.
Written by Sally LaMont, ND, LAc, Contributing Writer
One of the most exciting advances to emerge from the public’s heightened awareness of celiac disease and gluten sensitivity is the rediscovery of ancient, gluten-free, heirloom seeds and grains. Himalayan Tartary Buckwheat (Fagopyrum tataricum) – a naturally gluten-free variety of buckwheat–-is an excellent example of such a rediscovery. This nutrient-rich strain of buckwheat originated in […]
“People who suffer from chronic elevated uric acid tend to harbor unhealthy biomes,” says neurologist David Perlmutter, MD.
In his latest book, Drop Acid: The Surprising New Science of Uric Acid, Perlmutter presents several studies showing that adverse changes in the gut microbiome directly relate to our ability to metabolize and eliminate uric acid (UA).
The intricate interplay between hyperuricemia and the gut microbiome is still a relatively new field of research. But it has already led to some interesting discoveries.
could be just what your patients need for a better life. Pre- and probiotics
have become mainstream solutions for improved overall wellbeing, but research
has revealed that paraprobiotics–heat-killed probiotic strains–can also have
very specific benefits. Paraprobiotics also deliver the added advantage of a
longer shelf-life without the need for refrigeration.
free webinar, Danielle Citrolo, PharmD, and Shintaro Ichikawa, PhD, will
discuss how paraprobiotics will benefit your patients. They will introduce you
to IMMUSE and EYEMUSE, two branded forms of clinically studied strains that help
to bolster immune function and vision by stimulating immune cells within the
gut and the retina. IMMUSE is currently supported by eleven human trials and
EYEMUSE is supported by two studies.
webinar, you will:
understanding of what are paraprobiotics, and why they could be a good
alternative to probiotic strains in your practice.
importance of the immune system and its role in overall health.
the ability of paraprobiotics to influence the immune system for improved
the published clinical research behind the unique paraprobiotic strains used
for IMMUSE and EYEMUSE.
Citrolo, PharmD is a registered pharmacist who
provides scientific and regulatory support to
Kyowa’s customers in the US, Canada and Latin America. She holds degrees in
biochemistry and chemistry from North Carolina State University and a Doctor of
Pharmacy from Albany College of Pharmacy, NY.
Ichikawa, PhD, is the Director of Technical Affairs
at Kyowa Hakko USA. He is leading the launch of IMMUSE™, the company’s unique
Lactococcus lactis strain, in the United States. He previously led the launch
of IMMUSE™ in Japan. Dr. Ichikawa holds a Doctorate in Life Science from the
University of Tokyo, Department of Applied Biochemistry.