The search for longevity has moved from myth to molecular science. In this eye-opening presentation, we explore groundbreaking research revealing how telomerase activity and epigenetic modifications may hold the keys to slowing—and even reversing—the aging process.

Once thought to function solely by extending telomeres, telomerase is now recognized for its non-canonical roles in gene expression, mitochondrial function, and DNA repair. Insights emerging from landmark studies on the reversibility of epigenetic drift, suggests a future in which aging is not inevitable, but modifiable through small molecule telomerase activators.

Join Dr. Joseph Raffaele and learn how these discoveries are reshaping our clinical understanding of lifespan, healthspan, and regenerative potential.

Learning Objectives:

• Understand the multiple roles of telomerase in both telomere maintenance and its lesser-known functions in regulating cell biology and metabolism.
• Review the mechanisms by which epigenetic changes contribute to aging—and how partial reprogramming may restore youthful gene expression profiles.
• Analyze the findings of key animal studies, including those demonstrating reversal of age-related decline through transient telomerase activation or epigenetic reset.
• Discuss the translational potential of these discoveries for human aging, including therapeutic strategies and clinical biomarkers of rejuvenation.

SPONSORED BY T.A. SCIENCES

Joseph Raffaele, MD received his B.A. in philosophy from Princeton University and his MD from Drexel University Medical School in 1989. Board-certified in internal medicine, Dr. Raffaele trained at The New York Hospital/Weill Cornell University Medical Center. He is a diplomat of the American Board of Anti-Aging Medicine.  Since 1997 he has exclusively practiced longevity medicine with a focus on personalized physiological age assessment and gerotherapeutics. In 2007, he co-founded PhysioAge Health Analytics, a web-based biomarker data collection and reporting system now used by longevity and integrative medicine practices around the world. He has published clinical research in telomere biology, epigenetics, and glycobiology.  In 2015 he founded Raffaele Medical, and he posts regularly about telomere biology, hormone optimization, and biomarkers of aging/longevity therapeutics at @Raffaelemd and PhysioAge.com.